Artist Georgia O'Keeffe moved to Santa Fe in 1949 and established it as her new home and artistic haven as it, according to O'Keeffe, expressed “the wideness and wonder of the world as I live in it.” Though she had been popular and recognized in New York art circles, she found her niche in the rugged New Mexican terrain where she immortalized flowers, shrubs, rocks, shells, and other natural objects through large-scale abstractions. The Georgia O'Keeffe Museum has over 3,000 works of art, including 1,149 paintings, drawings, and sculptures done by O'Keeffe from 1901 to 1984. The museum is also dedicated to O'Keeffe's contemporaries and the American contemporary and modernist art movements; artists such as Arthur Dove, Sherrie Levine, Jackson Pollock, and Andy Warhol have had their work displayed at the museum.

"Viva la Fiesta!" has rang across the streets of Santa Fe for nearly 300 years. Every fall since 1712, people have gathered in Old Santa Fe to celebrate Don Diego De Vargas' peaceful reoccupation of the City of Holy Faith in 1692. The fiesta incorporates both local and Native American traditions, making it one of Santa Fe's most storied and treasured attractions.

The Bill Williams River National Wildlife Refuge is found at the far reaches of southeastern Lake Havasu. Rumored to contain the largest surviving cottonwood-willow woodlands of the lower Colorado River, the Refuge covers 6,000 acres. Perhaps most importantly, the Bill Williams River serves as a comfortable refuge to over 300 species of birds and waterfowl. There are a number of endangered species currently in propagation, including the razorback sucker fish and bony-tail chubs, which are indigenous to the Bill Williams River. Additionally, the Audubon Society named the Refuge an area of global significance in 2011.