Located in the North Rhine-Westphalia region of the country, modern Dortmund is vibrant and cultural, known for its good shopping, beer and football. But there is another, altogether gentler, side to this former industrial powerhouse. Dortmund has great theatres and cultural centres, a range of fascinating museums and, with half the city given over to parks and gardens, enough green areas to sooth the senses.

Tirana is a mixture of Western Europe and old Russia, interspersed with influences from the Middle East. The city has overcome its recent troubled past and risen as a gem of Eastern Europe. The modern Tirana is full of restaurants, nightlife and hotels, and has rediscovered itself and become an energetic, vibrant and cosmopolitan city that it is worth exploring.

They all used to come here, from Coco Chanel and Ernst Hemingway to Frank Sinatra and the royals — Biarritz used to be the Monte Carlo of the Atlantic coast. But with time, the glamour faded. Thanks to windsurfing and other water sports, however, the charming city has rejuvenated. It is now the perfect destination for a relaxing weekend break, and there is no need to rush: the city is fairly small and you can easily see everything even on a short visit.

Murrells Inlet channels the charm of South Carolina with undertones of its colonial past and a menagerie of modern vacation amenities. As “The Seafood Capital of South Carolina,” Murrells Inlet welcomes visitors to explore its fishing enterprise. Not only is the seafood widely renowned, but so is the area’s collection of golf courses. But perhaps most spectacularly, Murrells Inlet is a nature lover’s paradise: Spanish moss drapes grand oaks that have stood for centuries, and seabirds glide over the sparkling waters of the Atlantic.

Sitting near the confluence of two great North American rivers — the Mississippi and the Missouri — the St. Louis region has been a favored destination since Lewis & Clark began their historic westward discovery here in 1804. Dubbed the “Gateway to the West,” St. Louis welcomes its visitors with the world’s tallest arch (630 ft.) which was completed in 1965 as a monument to Thomas Jefferson and the westward expansion of the United States.