Since 1929, the Heard Museum has been dedicated to preserving and celebrating Native American cultures with historical accuracy and cultural sensitivity. Collaborating closely with Native communities, particularly those from the Southwest, the museum is renowned for its educational programs, immersive exhibits, and vibrant festivals. Visitors can explore stunning works of art, pottery, jewelry, textiles, and more, created by Native artists who offer their own, first-person perspectives on their traditions and history. The museum also hosts exciting annual events, such as the Heard Museum Guild Indian Fair & Market, which showcases Native art, music, and performances.

Housed in a former railway station, the Musée d'Orsay holds a mesmerising collection of mainly French paintings, sculptures, and photography, including the world's largest collection of impressionist and post-impressionist paintings, with works from artists such as Van Gogh, Cézanne, Renoir, and Monet.

The historic Orpheum Theatre in downtown Phoenix is a cultural gem, hosting a variety of performances from Broadway shows to comedy acts and live concerts. With its exquisite Spanish Baroque Revival décor, the theater’s lobby exudes old-world charm, while the 1,364-seat auditorium boasts grand columns and a stunning hand-painted ceiling that mimics a vibrant desert sunset. Over the years, the Orpheum has welcomed a wide range of talent, including renowned musicians like Bryan Adams and Feist, as well as comedians such as Lewis Black.