A rental car is the best way to explore Sicily. The road network is well maintained, especially the toll roads (autostrade). To drive in the city of Catania can be quite tricky though. A majority of the city centre is for pedestrians and parking lots are difficult to find.

An alternative to driving is travelling by train to Messina, Syracuse, Palermo and other cities from the station at Piazza Giovanni XXIII.

A cheaper mode of transport is the bus, which departs from the depot at Via d’Amico close to the train station. To get around in the city, the company AMT serves a number of lines. Bus tickets must be validated upon entering the bus (get them punched in the orange machine onboard).